Rome to Savona suggestions
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I have done this trip before.
The easiest way is to get the train from Central Rome through to Savona
Eurostar Italia has a direct service which takes just under 6 hours. I think by the time you add in the travelling and check in times etc at airports it is about the same.
There may well still be an overnight sleeper direct from Rome to Savona. I have done this. From memory it leaves Rome at around 2100 and arrives at Savona at 0700 nxt day.
www.trenitalia.it is good for information.
Cruises starting from/to Savona, Genoa normally provide shuttle services to Milan-Malpensa and Nice.
Genoa - Savona is easy going by train.
Bus to station and then train to Savona.
Milan-Malpensa - Savona
Option 1: Bus to Milan Central Station and then train to Savona
Option 2: Bus to Genoa PP Station and then train to Savona (but only once a day!)