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Covid-19 Vaccine Pfizer/BioNTech 90% Effective - Update 11/9/20


Formula280SS
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1 hour ago, Formula280SS said:

 

Likely on point.  Also, it looks like the first thing to consider when reading about "number of doses" that Pfizer is preliminarily disclosing will be available (and when) is that it appears that we have to "divide by 2" for the required 2-dose regimen of the vaccine?

 

 

Not only the double dose but also where it's going, the UK for instance pre-ordered 40 million doses months ago, I have no idea what other countries have also placed pre-orders of the vaccine.

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This is wonderful news.

 

It's still going to take some time, but the takeaway here is that there will be a vaccine and the pandemic will end and we will be cruising again!

 

I have high hopes for 2021. That first sailaway post-pandemic is going to be extra amazing.

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28 minutes ago, ziggyuk said:

 

Not only the double dose but also where it's going, the UK for instance pre-ordered 40 million doses months ago, I have no idea what other countries have also placed pre-orders of the vaccine.

 

Yep.  👍

 

I only made a partial reference to allocation to other contracting countries in a preceding post, but I just do not have and can not find the list or details. 

 

So, there are indeed quite a number of moving parts to the vaccine(s) as they become approved and then distributed in (at first) quite limited availability (also depending on doses per patient regimen).

 

But it looks brighter.

 

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17 hours ago, slavetoabunny said:

I am not an anti-vaxxer and yes, I do wear my mask.  I get my tetanus, etc. but I have not gotten a flu vaccination in 13 years (and haven't gotten the flu), and I will not be rushing out to get a brand spanking new vaccine anytime soon.  I've resigned myself to not cruising again for a long time.  With all the restrictions, it seems like you're paying a lot of money to be on a prison ship.  I've already cancelled two cruises and with the $10,000 in refunds I received am looking at alternatives.

I do get a flu vaccine, and plan on getting the vaccine when it is ready- but do think that I will be a way off from getting back on  a cruise ship. I'll book last minute when the time comes for me in 2023-2024. Some of this was based on wanting a Breakaway + class ship with Howl at The Moon sailing from NYC vs. flying out to Seattle or Miami. 

My cruise this year would have been May- i worried about those on ships in March,

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2 hours ago, ziggyuk said:

 

Not only the double dose but also where it's going, the UK for instance pre-ordered 40 million doses months ago, I have no idea what other countries have also placed pre-orders of the vaccine.

The UK Government claim to be 'towards the front of the pack' for receiving our 40 million doses.

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2 hours ago, Formula280SS said:

 

I only made a partial reference to allocation to other contracting countries in a preceding post, but I just do not have and can not find the list or details. 

 

 

I don't know what how much is being developed at each site, but from this reading Pfizer is supposedly doing its own distribution and that it has two facilities (one in the USA and one in Belgium).

 

"The U.S. government tapped McKesson Corp. to distribute future vaccines, except for the one from Pfizer, which is doing it on its own. 

 

In Kalamazoo, Mich., Pfizer has turned a stretch of land the size of a football field into a staging ground outfitted with 350 large freezers, ready to take delivery of millions of doses of Covid-19 vaccine before they can be shipped around the world. From that site, and another in Puurs, Belgium, the pharmaceutical giant said it wants to deliver up to 100 million doses this year and another 1.3 billion in 2021."

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36 minutes ago, hamrag said:

The UK Government claim to be 'towards the front of the pack' for receiving our 40 million doses.

 

Who knows, we have apparently got 300 million doses (enough for 150 million) of 5 or 6 different candidates on order, that's with a population of just 66 million.
I know we not only advance ordered the Oxford vaccine but also advance funded it, I have no idea about the other candidates.

You probably know I am on the Oxford trial and I believe they are also close to an announcement, we have huge volumes of that vaccine coming and they have been in production and stockpiling for some time.

I think all the governments probably think they are first in line with their commercial arrangements. it will more likely be an even split between interested parties. 

 

The German Government funded the clinical trial and manufacturing of the Pfizer vaccine so they will probably have first dibs.

Who knows what contracts have been signed though.

Edited by ziggyuk
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2 hours ago, Formula280SS said:

Yep.  👍

I only made a partial reference to allocation to other contracting countries in a preceding post, but I just do not have and can not find the list or details. 

 

With everyone desperate and with advance orders how much of that 100 million shots produced this year will each country get?
I found this:

image.png.aa5feae2e57d8e1b17c5928dd2c53956.png

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23 hours ago, Capitan Obvious said:

 

 

This may seem like a radical idea, but instead of saying "I have never understood people who...", might it be better to do some research and find out the "why" of it? You might learn something, and even if you disagree, you'll at least understand what is behind their position.

Might seem like a radical idea but have you ever considered that some people may do research before making the “I have never understood” statement?   I’ve done my research (person to person, online) and still don’t understand the logic of those people who don’t want vaccines.  

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It's comforting to know I have a 45% chance of Being immune. I'm in the Pfizer phase 2/3 study. 50-50 chance I got vaccine, 90% effective....I'll take it!

 

And my DW is one who has previously said she won't take the vaccine due to the short approval cycle. An RN by the way. And only takes the flu vaccine when required to by work. She's not an anti-vaxxer by any stretch of the imagination. She did support me getting in the trial. We haven't discussed it recently, she may have changed her mind on taking it.

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1 hour ago, Laszlo said:

Keep in mind people their is very likely to be at least a half dozen more vaccines coming online in the next 2-3 months. The big question will be is which one to get with all things being equal

 

More interesting is short term press doesn't imply long term health effects or efficacy will hold.  Sadly the one that is first gets all the press but hopefully doesn't detract from the other efforts.    Unlike somethings there might be more than one good cure.

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2 hours ago, Laszlo said:

Keep in mind people their is very likely to be at least a half dozen more vaccines coming online in the next 2-3 months. The big question will be is which one to get with all things being equal

with limited availability, not sure that anyone will have the option of "going shopping".

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44 minutes ago, chipmaster said:

 

More interesting is short term press doesn't imply long term health effects or efficacy will hold.  Sadly the one that is first gets all the press but hopefully doesn't detract from the other efforts.    Unlike somethings there might be more than one good cure.

I also hope it stays at 90% as they will have another reading after 163 cases. As of now approximately 8 or 9 of the 93 had the vaccine and 84-85 the placebo. However, what concerns me is these people were likely acting very responsibly, there is no true measure of how the vaccine would perform under normal conditions (i.e. no masks, no distancing)

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14 hours ago, hamrag said:

How about coining a new word for such.....vacc-idiot!

Well, this vacc-idiot says 'go for it' if you believe everything you're told by the so called experts and politicians. I would never consider taking a vaccine delivered in such a short period of time.

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1 hour ago, winterbliss said:

Well, this vacc-idiot says 'go for it' if you believe everything you're told by the so called experts and politicians. I would never consider taking a vaccine delivered in such a short period of time.

 

Never? You do realize that in order for you to state that you wouldn't take a vaccine because of the short delivery time that you already have considered it? It is that very consideration that allows you to choose to not take the vaccine.

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15 hours ago, dcipjr said:

This is wonderful news.

 

It's still going to take some time, but the takeaway here is that there will be a vaccine and the pandemic will end and we will be cruising again!

 

I have high hopes for 2021. That first sailaway post-pandemic is going to be extra amazing.

It is good news about the vaccine; however, it’s unlikely any ships will sail from the U.S. in 2021 based upon the projected results of the presidential election. 

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6 hours ago, winterbliss said:

Well, this vacc-idiot says 'go for it' if you believe everything you're told by the so called experts and politicians. I would never consider taking a vaccine delivered in such a short period of time.

 

Everyone has varying levels of risk tolerance.  Pick your poison.  No judgements from me. 

 

We are going to opt for the vaccine.  Our family has a case of "covid precaution fatigue".  We are finding it harder to stay 100% focused on maintaining covid protocols.  Additionally we have family members who are in the high risk category. 

 

Our thought process: 

 

Roll the dice and hope covid doesn't strike our family or we get the new vaccine.  Covid has many knowns.  The vaccine has many unknowns.  

 

Besides the potential of hospitalization and/or death we have to weigh covid's sometime long-term health effects (Depression, heart palpitations, inflammation of the heart muscle, lung function abnormalities, acute kidney injury, smell and taste problems, sleep issues, difficulty with concentration, memory problems). 

 

Or we take a calculated risk on a vaccine that 9 months into the trial has shown no significant side effects.  No absolute guarantee there won't be vaccine related health issues later on. 

 

FDA's Vaccines and Related Biological Products Advisory Committee, which consists of 15 members who are infectious disease specialists at universities and research centers will review the vaccine trial data.  The advisory committee's recommendation will be forwarded to the FDA's Center for Biologics Evaluation and Research, and then to FDA Commissioner for emergency approval.  I trust in the non-political scientist's judgement.  I trust in science and biology.      

 

If covid wasn't such a nasty virus I would wait, but unfortunately it's not.  Vaccine for me and living life to follow.   

   

 

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9 hours ago, Capitan Obvious said:

 

Never? You do realize that in order for you to state that you wouldn't take a vaccine because of the short delivery time that you already have considered it? It is that very consideration that allows you to choose to not take the vaccine.

Wow, that was really obvious Captain Obvious. Thanks!

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19 hours ago, Formula280SS said:

 

I don't know what how much is being developed at each site, but from this reading Pfizer is supposedly doing its own distribution and that it has two facilities (one in the USA and one in Belgium).

 

"The U.S. government tapped McKesson Corp. to distribute future vaccines, except for the one from Pfizer, which is doing it on its own. 

 

In Kalamazoo, Mich., Pfizer has turned a stretch of land the size of a football field into a staging ground outfitted with 350 large freezers, ready to take delivery of millions of doses of Covid-19 vaccine before they can be shipped around the world. From that site, and another in Puurs, Belgium, the pharmaceutical giant said it wants to deliver up to 100 million doses this year and another 1.3 billion in 2021."

Cool 😎. Kalamazoo is just down the highway from me in Muskegon. Maybe I can be the 1st in line for the new vaccine. (Just kidding - please don't flame me).

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13 hours ago, HowardK said:

I also hope it stays at 90% as they will have another reading after 163 cases. As of now approximately 8 or 9 of the 93 had the vaccine and 84-85 the placebo. However, what concerns me is these people were likely acting very responsibly, there is no true measure of how the vaccine would perform under normal conditions (i.e. no masks, no distancing)

I realize we may not be typical, but here's our life:

* I'm driving 20 hours each way to California this weekend because I don't want to spend 6 hours in a mask while making two flight legs.

* Making the choice to lose weight has had much more bearing on how much we eat in restaurants than any COVID restriciton. We pciked up 5-6 days a week when the restaurants were pick up or drive through only.

* I only wear mask where required, and the second I can say it's no longer required, off it comes. Example, put it on in the car before going to the convenience store, take it off before the door even swings shut on my way out.

* My daughter is a high schooler, attending school face to face right now. They go back to online only next week due to COVID spread in the community.

* My wife transports COVID patients at her job. She maintains proper PPE while transporting a COVID  patient, but the rest of the time, not so much. 

* She stays in hotels on her days off about half the time and comes home the other half. I go to the hotel with her one weekend a month.

 

I try to maintain polite distance, but rarely the full six feet. 

 

All this to say, I'm not sure it can be accurately asserted that trial participants are acting very responsible. In my case the vaccine trial has made no difference at all in my actions.

 

The point that it has not been tested in the no mask/no distancing community has validity. There has been a lot of ethical discussion about whether to accept paid volunteers to be vaccinated and purposely exposed.

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4 hours ago, mianmike said:

If covid wasn't such a nasty virus I would wait, but unfortunately it's not.  Vaccine for me and living life to follow.   

  

 

Agreed. I will likely get the vaccine when it becomes available, since I don't know if I have the vaccine or placebo. Doing so would end my trial participation, so I may elect to wait until the trial ends in early 2022.

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https://www.msn.com/en-us/news/politics/cdc-report-says-masks-now-protect-wearer-as-well-as-the-public/ar-BB1aSZT5?li=BBnb7Kz

 

Why did it take them so long to figure this out?  I have been asking this question since March.  If masks protect the other person from my droplets getting out, why would they not protect me from others getting in?? 

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50 minutes ago, plainsstormchaser said:

Agreed. I will likely get the vaccine when it becomes available, since I don't know if I have the vaccine or placebo. Doing so would end my trial participation, so I may elect to wait until the trial ends in early 2022.

 

I'm on the Oxford Trial and I asked them what would happen if I was offered a competitors vaccine before the trial ended as I was not willing to endanger my life if I had the option of a vaccine.
I was told, if the situation arose, I would be told if I had received the vaccine or placebo as it would be unethical not to do so.

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