I don't think so, Rome is quite large with so many hotels, I'm not sure you could tell the difference.  For the past two years it has been crowded, pretty much all the time.  In late November last year the "in" restaurants all required reservations for lunch and dinner, in our case made by my travel partner weeks in advance.   The Vatican museums are a zoo every single day of the year that they are open,and have been for years.  If it's important to you, and within your budget, I highl