These suggestions are all great - that's why I love Cruise Critic!!! I agree if all adult travelers, do three smaller suitcases and cross pack. I also keep our CPAPs and a small rolling carry on with us - pack things I don't want to check but also don't want to lug too much around the ship until our cabin is ready!! Think iPad & charger, meds, jewelry, bathing suit if warm climate cruise, light sweater if cool climate cruise, small sunscreen container - essentials/valuables. This approach is also helpful at the end of the cruise. I leave our regular luggage outside the door on the last night for pick up and keep the small roller/carry-on bag for essentials/valuables along with the CPAPs to debark the next morning. Hope this helps... enjoy your cruise! The luggage with four wheels that swivel 360 degrees have saved my back and shoulders immensely in all forms of travel!!!! Great invention