Yes we can easily manage our luggage. Just went 1.3km both ways on old brick roads and sidewalks from the ferry on Isla Mujeres to our hotel without issues. What do you mean which schedule works for me? We cruise into Trieste. And need to arrange transport to Venice as we decided to stay there for an extra night and fly out of Venice the next afternoon
We have a similar time frame and are planning to go to the Acropolis and museum, Temple of Zeus, walk around the Plaka and Monastiraki Flea Market, and then also do an e-bike tour of the city at night, which was recommended by someone I know.
I think between the two of us we will have one medium sized roller suitcase and two small carry on size. Problem is, my husband packs more than me! I'm gonna try to downsize a little tonight.