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About orville99

  • Rank
    5,000+ Club

About Me

  • Location
    Orlando area in Florida
  • Interests
    cooking, fishing, cruising
  • Favorite Cruise Line(s)
    Royal Caribbean, Holland American
  • Favorite Cruise Destination Or Port of Call
    Caribbean, Alaska

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  1. We figure our March cruise is a no go, and that our mid-May one is the first one we'll actually get to cruise. We're both first responders and over 65, so hopefully we'll be vaccinated by then.
  2. Any vaccine that meets the safety and efficacy benchmark set by the EMA and the FDA will be approved. No single vaccine can be produced in the quantity or at the speed necessary to vaccinate 8+ billion people world-wide, let alone the 340 million in the U.S. or the 70 million in the U.K. No approval agency with any ethical backbone would ever cherry-pick the winners and losers, because that would mean making the choice of who lives and who dies. If that behavior were even remotely possible, there would never have been a Sabin vaccine for Polio, or a Tamiflu for influenza. Whether a particular
  3. Not in the least. You really have to do a bit of research so you can understand how the approval process works. If your logic held any water, there would never be multiple flu vaccines, or any other competitive entrants into the pharmaceutical marketplace. If governments (any government) ever said "we have a good solution to this ailment, so no one else needs to pursue any more research", the entire pharma industry would collapse, and there would ultimately be no solutions for any future ailment. I realize that your options are dictated by your NHS, but it is a free market over her
  4. Any country can limit the entry choices of anyone entering their country if that entry presents a public health hazard. As I said earlier, before smallpox was declared to have been eradicated, the entry requirements into the U.S. were both very strict and very closely enforced. Could I have returned without proof of vaccination, yes, but I would have had to be quarantined (not at home, but wherever the government ordered me to quarantine) for an extended period of time. Governmental leverage is just that - leverage. The government says here are your choices, and we can't make your choice for y
  5. The only place less likely to have valid information on anything than a U.S. politician, is a U.S. social media site. You do realize that Yahoo "news" merely aggregates whatever is floating around on the rest of the social media world. There is absolutely no validity to any claim that the FDA will or will not approve any investigational medication. Data are data, and data will ultimately make the decision, not Yahoo or a political hack. BTW, the U.S. has $1.2Bn (300 million doses) of the AZ vaccine on its order books, so if and when the data show that the vaccine meets the efficacy
  6. Agree, but there is a difference between willing and needing, and governmental leverage to influence need is quite common. Back when smallpox was raging, we in the U.S. were not mandated to get the vaccine, and a significant number of people (me included) were not willing to get it. That changed when my career required me to travel outside the U.S. While I was not required to get the vaccine before I left the U.S. for Europe, I was prohibited from re-entering the U.S. without a proof of vaccination. No one is mandated to get any vaccine in the U.S., but students in public school systems in the
  7. I personally would not take anything said by a U.S. politician as fact. I doubt she could even tell you which agency actually has approval authority in Europe or the U.K. The EMA and FDA are on the same page, and those two agencies are the ones that approve drugs, not a politician from California. BTW, the U.S. gave AZ $1.2Bn to pre-purchase 300 million doses of the vaccine once it is approved. I would be more concerned with the fact that the AZ clinical trials have only enrolled ~3,000 people in the U.K.,and ~8,000 in Brazil so they may not have sufficient data to meet the level
  8. The press on both the AZ and J&J vaccines has not been bad in any way. Pauses in clinical trials are both expected and routine, and happen with virtually any new drug in a double blind placebo-controlled study. Not sure how the pauses were presented in the U.K. press, but they have never been portrayed in a negative light in the U.S. press.
  9. For starters, the CDC has no role in the approval of vaccines (or any other drugs) in the U.S., that is the sole purview of the FDA. The FDA will review and approve or reject any new drug application based solely on its own merits. The relative efficacy of competing drugs doesn’t enter into their decision process.
  10. Not exactly. The data has already been delivered to the FDA and the independent review panel. They will take the next two weeks to pour over the data and then on 12/9-12/10 they will meet to discuss their individual findings and take a vote whether to tell the FDA to proceed with the EUA or to kick the whole study back for more data. The FDA can then either take the committee's recommendation or reject it based on their own review of both the data and the committees findings. SOP for any new drug approval by the FDA.
  11. Given that they can't explain the discrepancy, this vaccine candidate is probably a lot farther away from certifiable than either Pfizer or Moderna's. Regulating agencies need definable consistent results, and "we don't know" or "we're not sure" generally doesn't cut it.
  12. Our next RCL cruise in the cross-hairs is at the end of March, and final payment date is at the end of December, so we're hanging tight until we have to make that payment to decide. If they cancel after that, we still have the L&S option for 2022 available, or we'll take the refund option. We have 14 booked cruises now, and there aren't a lot of holes in the schedule to stuff in any more L&S cruises.
  13. I went back and checked on all six cruises that were either cancelled by RCL or that I cancelled with CWC, and I got everything back either as an FCC, a refund, or a L&S move (including the travel insurance $$). Maybe the problem has something to do with when the cancellations occurred relative to the final payment date? My understanding is that insurance isn't in effect until after the final payment date, so if the cancellation occurred prior to that date, it really hasn't been invoiced yet.
  14. Had this problem on a Bermuda cruise we booked on Monday. When we received the booking invoice there was no balcony discount even though the online booking system said it would be applied. Called the C&A D+ deck and it took a supervisor to get it added. She said that there was a glitch in the system and that several promos weren’t being applied properly. Emailed me about 20 minutes later with a corrected invoice.
  15. Just recognize that the ultimate decision on whether balcony dividers can be opened rests with the captain. We've been on Voyager and Freedom class ships that have the openable dividers, but the captain had made the decision not to allow them to be opened. We've been on the same ships with a different captain where the balcony dividers were allowed to be opened.
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